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Index > Protein center > IL20RA(Gene name) > Human
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  • IL20RA (Gene name),
  • Interleukin-20 receptor subunit alpha (Protein name ),  I20RA_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    IL20RA(UNQ681/PRO1315);
    Protein name:
    Interleukin-20 receptor subunit alpha(IL-20 receptor subunit alpha;IL-20R-alpha;IL-20RA);
    Alternative:
    Cytokine receptor family 2 member 8(CRF2-8);Cytokine receptor class-II member 8;ZcytoR7;IL-20R1;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Heterodimer with IL20RB and heterodimer with IL10RB.
    Function:
    The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL20RA/IL10RB dimer is a receptor for IL26.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    553
    Sequence:
    50:
    MRAPGRPALR | PLPLPPLLLL | LLAAPWGRAV | PCVSGGLPKP | ANITFLSINM | 
    100:
    KNVLQWTPPE | GLQGVKVTYT | VQYFIYGQKK | WLNKSECRNI | NRTYCDLSAE | 
    150:
    TSDYEHQYYA | KVKAIWGTKC | SKWAESGRFY | PFLETQIGPP | EVALTTDEKS | 
    200:
    ISVVLTAPEK | WKRNPEDLPV | SMQQIYSNLK | YNVSVLNTKS | NRTWSQCVTN | 
    250:
    HTLVLTWLEP | NTLYCVHVES | FVPGPPRRAQ | PSEKQCARTL | KDQSSEFKAK | 
    300:
    IIFWYVLPVS | ITVFLFSVMG | YSIYRYIHVG | KEKHPANLIL | IYGNEFDKRF | 
    350:
    FVPAEKIVIN | FITLNISDDS | KISHQDMSLL | GKSSDVSSLN | DPQPSGNLRP | 
    400:
    PQEEEEVKHL | GYASHLMEIF | CDSEENTEGT | SLTQQESLSR | TIPPDKTVIE | 
    450:
    YEYDVRTTDI | CAGPEEQELS | LQEEVSTQGT | LLESQAALAV | LGPQTLQYSY | 
    500:
    TPQLQDLDPL | AQEHTDSEEG | PEEEPSTTLV | DWDPQTGRLC | IPSLSSFDQD | 
    550:
    SEGCEPSEGD | GLGEEGLLSR | LYEEPAPDRP | PGENETYLMQ | FMEEWGLYVQ | 
    553:
    MEN
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    SMR:
    KEGG:
    Pfam:
    String:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human IL-20 receptor subunit alpha
    Cat.:
    E1004m
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human IL-20 receptor subunit alpha
    Cat.:
    E1004h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human IL-20 receptor subunit alpha
    Cat.:
    U1004h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human IL-20 receptor subunit alpha
    Cat.:
    U1004m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human IL-20 receptor subunit alpha
    Cat.:
    P1004Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human IL-20 receptor subunit alpha
    Cat.:
    P1004Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human IL-20 receptor subunit alpha
    Monoclonal Antibody for Human IL-20 receptor subunit alpha
    Protein for Human IL-20 receptor subunit alpha
    Protein for Human IL-20 receptor subunit alpha

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Homo sapiens cytokine receptor homolog."
      Lok S. , Kho C.-J. , Jelmberg A. , Adams R. , Whitmore T. , Farrah T. , O'Hara P.
      Submitted (1999-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANTS ILE-259 AND PHE-382
    2. 2.
      "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
      Clark H.F. , Gurney A.L. , Abaya E. , Baker K. , Baldwin D.T. , Brush J. , Chen J. , Chow B. , Chui C. , Crowley C. , Currell B. , Deuel B. , Dowd P. , Eaton D. , Foster J.S. , Grimaldi C. , Gu Q. , Hass P.E. , more...
      Genome Res.13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2);VARIANT ILE-259
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3);VARIANT ILE-259
      tissue: Fibroblast.
    4. 4.
      "The DNA sequence and analysis of human chromosome 6."
      Mungall A.J. , Palmer S.A. , Sims S.K. , Edwards C.A. , Ashurst J.L. , Wilming L. , Jones M.C. , Horton R. , Hunt S.E. , Scott C.E. , Gilbert J.G.R. , Clamp M.E. , Bethel G. , Milne S. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Andrews T.D. , more...
      Nature425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA];VARIANT ILE-259
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT ILE-259
      tissue: Brain.
    7. 7.
      "Signal peptide prediction based on analysis of experimentally verified cleavage sites."
      Zhang Z. , Henzel W.J.
      Protein Sci.13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 30-44
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT;LIGAND-BINDING;TISSUE SPECIFICITY
    9. 9.
      "STAT activation by IL-19, IL-20 and mda-7 through IL-20 receptor complexes of two types."
      Dumoutier L. , Leemans C. , Lejeune D. , Kotenko S.V. , Renauld J.-C.
      J. Immunol.167:3545-3549(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: LIGAND-BINDING
    10. 10.
      "Interleukins 19, 20, and 24 signal through two distinct receptor complexes. Differences in receptor-ligand interactions mediate unique biological functions."
      Parrish-Novak J. , Xu W. , Brender T. , Yao L. , Jones C. , West J. , Brandt C. , Jelinek L. , Madden K. , McKernan P.A. , Foster D.C. , Jaspers S. , Chandrasekher Y.A.
      J. Biol. Chem.277:47517-47523(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT;LIGAND-BINDING
    11. 11.
      "Characterization of the recombinant extracellular domains of human interleukin-20 receptors and their complexes with interleukin-19 and interleukin-20."
      Pletnev S. , Magracheva E. , Kozlov S. , Tobin G. , Kotenko S.V. , Wlodawer A. , Zdanov A.
      Biochemistry42:12617-12624(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT;LIGAND-BINDING
    12. 12.
      "IL-26 signals through a novel receptor complex composed of IL-20 receptor 1 and IL-10 receptor 2."
      Sheikh F. , Baurin V.V. , Lewis-Antes A. , Shah N.K. , Smirnov S.V. , Anantha S. , Dickensheets H. , Dumoutier L. , Renauld J.-C. , Zdanov A. , Donnelly R.P. , Kotenko S.V.
      J. Immunol.172:2006-2010(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT;LIGAND-BINDING;TISSUE SPECIFICITY
    13. 13.
      "Structural basis for receptor sharing and activation by interleukin-20 receptor-2 (IL-20R2) binding cytokines."
      Logsdon N.J. , Deshpande A. , Harris B.D. , Rajashankar K.R. , Walter M.R.
      Proc. Natl. Acad. Sci. U.S.A.109:12704-12709(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS) OF 29-245 IN COMPLEX WITH IL20RB AND IL20;SUBUNIT;DISULFIDE BONDS
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